RESUMO
We report the direct observation of muon neutrino interactions with the SND@LHC detector at the Large Hadron Collider. A dataset of proton-proton collisions at sqrt[s]=13.6 TeV collected by SND@LHC in 2022 is used, corresponding to an integrated luminosity of 36.8 fb^{-1}. The search is based on information from the active electronic components of the SND@LHC detector, which covers the pseudorapidity region of 7.2<η<8.4, inaccessible to the other experiments at the collider. Muon neutrino candidates are identified through their charged-current interaction topology, with a track propagating through the entire length of the muon detector. After selection cuts, 8 ν_{µ} interaction candidate events remain with an estimated background of 0.086 events, yielding a significance of about 7 standard deviations for the observed ν_{µ} signal.
RESUMO
Staphylopeptides with molecular weight less than 4000 Da, possessing their own specific allergic activity in skin allergic tests. immunoleukolysis test and phagocytosis breaking test were obtained by the acid extraction method.
Assuntos
Peptídeos/farmacologia , Staphylococcus aureus/imunologia , Alérgenos/imunologia , Alérgenos/isolamento & purificação , Alérgenos/farmacologia , Animais , Cobaias , Concentração de Íons de Hidrogênio , Peso Molecular , Neutrófilos/efeitos dos fármacos , Neutrófilos/imunologia , Peptídeos/imunologia , Peptídeos/isolamento & purificação , Fagocitose/efeitos dos fármacos , Fagocitose/imunologia , Testes CutâneosRESUMO
In gel-filtration of Cl. perfringens type A toxin on Sephadex F-100 and F-50 there was revealed relationship between the leukotoxic activity and a high-molecular component. A method of ion-exchange chromatography on a column with DEAE-Sephadex A-25 from the Cl. perfringens toxin there were obtained 8 fractions 3 of which possessed a marked leukotoxic activity: the capacity to destroy neutrophils in the Svejcar and Vancurik test and to-depress the phagocytic activity of leukocytes. Lecithinase and lethal activity was revealed in one of these fractions only. Leukotoxic fractions differed by the capacity to destroy neutrophils and to decrease their phagocytic activity.
